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William Howard Stein

William Howard Stein
William Howard Stein.jpg
Born(1911-06-25)June 25, 1911
New York City, New York, USA
DiedFebruary 2, 1980(1980-02-02) (aged 68)
New York City, New York, USA
EducationHarvard University
Columbia University
Spouse(s)Phoebe Hockstader (1936–1980; his death; 3 children)[1] (1913–1989)
AwardsNobel Prize in Chemistry (1972)
Scientific career
InstitutionsRockefeller University

William Howard Stein (June 25, 1911 – February 2, 1980) was an American biochemist.

Life and career

Stein was born and died in New York City. He was the son of a Jewish couple, Beatrice Cecilla (Borg), a children's rights activist, and Fred Michael Stein, a banker.[2] He was educated at Phillips Exeter Academy, Harvard University and Columbia University. He was a subsequently a researcher under Max Bergmann at Rockefeller University, where much of his most important work was done.[3]

Stein won a Nobel Prize in Chemistry in 1972 with Christian Boehmer Anfinsen and Stanford Moore, for their work on ribonuclease and for their contribution to the understanding of the connection between chemical structure and catalytic activity of the ribonuclease molecule.

In 1958 he and Stanford Moore developed the first automated amino acid analyzer, which facilitated the determination of protein sequences. Stein remained at Rockefeller for his entire career, and held visiting professorships at Washington University at St. Louis, Haverford College, the University of Chicago and Harvard University.[3]


  1. ^ "Phoebe H. Stein, 75, Health-Care Advocate". The New York Times. 1989-01-03.
  2. ^ []
  3. ^ a b "Nobel Prize Autobiography, William Howard Stein".

External links

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