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Uldazepam

Uldazepam
Uldazepam.svg
Clinical data
Synonyms7-chloro-5-(2-chlorophenyl)-N-prop-2-enoxy-3H-1,4-benzodiazepin-2-amine
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H15Cl2N3O
Molar mass360.24 g/mol g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2][3]

Synthesis

Thio thionamide is even more prone to amidine formation than the lactam itself.

Uldazepam synthesis: J. B. Hester, Jr., DE 2005176  (1970); Chem. Abstr., 73: 99,001t (1970).

Rxn of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.

See also

References

  1. ^ "Uldazepam U 31920". Psychotropics. Retrieved 12 June 2013.
  2. ^ Oelschläger H, Ellaithy MM, Volke J. Mechanism of the polarographic reduction of the tranquilizer uldazepam. (German). Archiv der Pharmazie (Weinheim). 1988 Feb;321(2):69-72.
  3. ^ Itil TM, Akpinar S, Ozkut H, et al.: Clinical and computerized EEG effects of U-31,920 a new anxiolytic. Current Therapeutic Research. 1974; 16: 642-654.