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Tarextumab

Tarextumab
Monoclonal antibody
Type?
SourceHuman
TargetNotch 2, Notch 3
Clinical data
Other namesOMP-59R5
ATC code
  • none
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6338H9804N1700O1990S48
Molar mass143196.94 g·mol−1

Tarextumab (formerly OMP-59R5) is a fully human monoclonal antibody targeting the Notch 2/3 receptors. It is being tested as a possible treatment for cancer. In Jan 2015 the US FDA granted orphan drug designation to tarextumab for the treatment of pancreatic cancer and lung cancer.[1] Two early stage clinical trials have reported encouraging results.[1]

See also

References

  1. ^ a b "Tarextumab Gets FDA Orphan Drug Designation for Lung, Pancreatic Cancer". 2015.