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TRPM6

TRPM6
Identifiers
AliasesTRPM6, CHAK2, HMGX, HOMG, HOMG1, HSH, transient receptor potential cation channel subfamily M member 6
External IDsOMIM: 607009 MGI: 2675603 HomoloGene: 9767 GeneCards: TRPM6
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for TRPM6
Genomic location for TRPM6
Band9q21.13Start74,722,495 bp[1]
End74,888,094 bp[1]
RNA expression pattern
PBB GE TRPM6 221102 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001177310
NM_001177311
NM_017662

NM_153417

RefSeq (protein)

NP_001170781
NP_001170782
NP_060132

NP_700466

Location (UCSC)Chr 9: 74.72 – 74.89 MbChr 19: 18.75 – 18.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119121 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024727 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schlingmann KP, Weber S, Peters M, et al. (2002). "Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family". Nat. Genet. 31 (2): 166–70. doi:10.1038/ng889. PMID 12032568.

Further reading

  • Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6.
  • Chubanov V, Gudermann T, Schlingmann KP (2006). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis". Pflügers Arch. 451 (1): 228–34. doi:10.1007/s00424-005-1470-y. PMID 16075242.
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.
  • Bödding M (2007). "TRPM6: A Janus-like protein". Handb Exp Pharmacol. 179 (179): 299–311. doi:10.1007/978-3-540-34891-7_18. PMID 17217065.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.