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TAS2R8

TAS2R8
Identifiers
AliasesTAS2R8, T2R8, TRB5, taste 2 receptor member 8
External IDsOMIM: 604794 HomoloGene: 88894 GeneCards: TAS2R8
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for TAS2R8
Genomic location for TAS2R8
Band12p13.2Start10,806,051 bp[1]
End10,807,293 bp[1]
RNA expression pattern
PBB GE TAS2R8 221398 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_023918

n/a

RefSeq (protein)

NP_076407

n/a

Location (UCSC)Chr 12: 10.81 – 10.81 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Taste receptor type 2 member 8 is a protein that in humans is encoded by the TAS2R8 gene.[3][4][5]

Function

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[5]

See also

References

  1. ^ a b c ENSG00000121314, ENSG00000272712 GRCh38: Ensembl release 89: ENSG00000277316, ENSG00000121314, ENSG00000272712 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell. 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934.
  4. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature. 404 (6778): 601–4. doi:10.1038/35007072. PMID 10766242.
  5. ^ a b "Entrez Gene: TAS2R8 taste receptor, type 2, member 8".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.