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Somatostatin receptor 4

SSTR4
Identifiers
AliasesSSTR4, SS-4-R, SS4-R, SS4R, Somatostatin receptor 4
External IDsOMIM: 182454 MGI: 105372 HomoloGene: 20286 GeneCards: SSTR4
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SSTR4
Genomic location for SSTR4
Band20p11.21Start23,035,386 bp[1]
End23,036,812 bp[1]
RNA expression pattern
PBB GE SSTR4 214556 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001052

NM_009219

RefSeq (protein)

NP_001043

NP_033245

Location (UCSC)Chr 20: 23.04 – 23.04 MbChr 2: 148.4 – 148.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene.[5][6]

Function

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.[6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132671 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037014 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rohrer L, Raulf F, Bruns C, Buettner R, Hofstaedter F, Schüle R (May 1993). "Cloning and characterization of a fourth human somatostatin receptor". Proceedings of the National Academy of Sciences of the United States of America. 90 (9): 4196–200. doi:10.1073/pnas.90.9.4196. PMC 46473. PMID 8483934.
  6. ^ a b "Entrez Gene: SSTR4 somatostatin receptor 4".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.