Minor involvement of CYP2D6 and CYP2A6
|Elimination half-life||5–7 hours|
|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||348.437 g/mol g·mol−1|
|3D model (JSmol)|
|(what is this?)|
Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis.
Pharmacodynamic studies showed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion.
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