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Olcegepant

Olcegepant
Olcegepant.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC38H47Br2N9O5
Molar mass869.645 g/mol g·mol−1
3D model (JSmol)

Olcegepant (INN,[1] code name BIBN-4096BS) is a calcitonin gene-related peptide receptor antagonist being studied as a potential treatment for migraines.[2]

A 2013 meta-analysis found olcegepant and telcagepant were effective and safe compared to placebo.[3]

See also

References

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 48" (PDF). World Health Organization. pp. 256–7. Retrieved 20 March 2017.
  2. ^ Tfelt-Hansen, P; Olesen, J (Apr 2011). "Possible site of action of CGRP antagonists in migraine". Cephalalgia : An International Journal of Headache. 31 (6): 748–50. doi:10.1177/0333102411398403. PMID 21383046.
  3. ^ Yao, Gang; Yu, Tingmin; Han, Ximei; Mao, Xijing; Li, Bo (2013-04-05). "Therapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis". Neural Regeneration Research. 8 (10): 938–947. doi:10.3969/j.issn.1673-5374.2013.10.009. ISSN 1673-5374. PMC 4145922. PMID 25206386.