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O-774

O-774
O-774 structure.png
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
FormulaC25H35NO2
Molar mass381.550 g/mol g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)

O-774 is a classical cannabinoid derivative which acts as a potent agonist for the cannabinoid receptors, with a Ki of 0.6 nM at CB1, and very potent cannabinoid effects in animal studies.[1][2]

See also

References

  1. ^ Singer M, Ryan WJ, Saha B, Martin BR, Razdan RK (October 1998). "Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol". Journal of Medicinal Chemistry. 41 (22): 4400–7. doi:10.1021/jm9803875. PMID 9784115.
  2. ^ Reggio PH, ed. (2009). "Cannabinoid Receptor Ligands and Structure-Activity Relationships.". The Cannabinoid Receptors. Part I. Humana Press. pp. 6–9. ISBN 978-1-58829-712-9.