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NM-2-AI structure.png
Clinical data
Other namesN-Methyl-2-aminoindane; AM-80
Legal status
Legal status
CAS Number
PubChem CID
Chemical and physical data
Molar mass147.22 g/mol g·mol−1
3D model (JSmol)

NM-2-AI (N-methyl-2-aminoindane) is a psychoactive drug and research chemical that has been sold online as a designer drug. It is a rigid analogue of methamphetamine.[1][2] It is a derivative of 2-aminoindane.

NM-2-AI acts as a non-neurotoxic and highly selective serotonin releasing agent (SSRA) in vitro and is a putative entactogen.[3]


  1. ^ "N-methyl-2-AI". Cayman Chemical. Retrieved 27 June 2015.
  2. ^ Joseph G. Cannon; Julio A. Perez; Jonathan P. Pease; John Paul Long; Jan R. Flynn; David B. Rusterholz; Stuart E. Dryer (July 1980). "Comparison of biological effects of N-alkylated congeners of .beta.-phenethylamine derived from 2-aminotetralin, 2-aminoindan, and 6-aminobenzocycloheptene". Journal of Medicinal Chemistry. 23 (7): 745–749. doi:10.1021/jm00181a009. PMID 7190613.
  3. ^ David E. Nichols; William K. Brewster; Michael P. Johnson; Robert Oberlender; Robert M. Riggs (February 1990). "Nonneurotoxic tetralin and indan analogs of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 33 (2): 703–710. doi:10.1021/jm00164a037. PMID 1967651.