This page uses content from Wikipedia and is licensed under CC BY-SA.
|Trade names||Primobolan, Primobolan S, Primonabol, Nibal|
|Synonyms||Methenolone acetate; NSC-74226; SH-567; SQ-16496; Methenolone 17β-acetate; 1-Methyl-δ1-4,5α-dihydrotestosterone 17β-acetate; 1-Methyl-δ1-DHT acetate; 1-Methylandrost-1,4-dien-17β-ol-3-one 17β-acetate|
|Drug class||Androgen; Anabolic steroid; Androgen ester|
|Chemical and physical data|
|Molar mass||g·mol−1 344.495|
|3D model (JSmol)|
Metenolone acetate, or methenolone acetate, sold under the brand names Primobolan and Nibal, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. It is taken by mouth. Although it was widely used in the past, the drug has mostly been discontinued and hence is now mostly no longer available. A related drug, metenolone enanthate, is given by injection into muscle.
Side effects of metenolone acetate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has moderate anabolic effects and weak androgenic effects, as well as no estrogenic effects or risk of liver damage. Metenolone enanthate is a metenolone ester and a prodrug of metenolone in the body.
Metenolone acetate was introduced for medical use in 1961. In addition to its medical use, metenolone acetate is used to improve physique and performance. The drug is a controlled substance in many countries and so non-medical use is generally illicit. It remains marketed for medical use only in a few countries, such as Japan and Moldova.
Metenolone acetate, or metenolone 17β-acetate, is a synthetic androstane steroid and a derivative of DHT. It is the C17β acetate ester of metenolone, which itself is 1-methyl-δ1-4,5α-dihydrotestosterone (1-methyl-δ1-DHT) or 1-methyl-5α-androst-1-en-17β-ol-3-one.
|Anabolic steroid||Structure||Ester||Rel. MWb||Rel. AASc||Durationd|
|Boldenone undecylenate||C17β||Undecylenic acid||Straight-chain fatty acid||11||1.58||0.63||Long|
|Drostanolone propionate||C17β||Propanoic acid||Straight-chain fatty acid||3||1.18||0.84||Short|
|Metenolone acetate||C17β||Ethanoic acid||Straight-chain fatty acid||2||1.14||0.88||Short|
|Metenolone enanthate||C17β||Heptanoic acid||Straight-chain fatty acid||7||1.37||0.73||Long|
|Nandrolone decanoate||C17β||Decanoic acid||Straight-chain fatty acid||10||1.56||0.64||Long|
|Nandrolone phenylpropionate||C17β||Phenylpropanoic acid||Aromatic fatty acid||– (~6–7)||1.48||0.67||Long|
|Trenbolone acetate||C17β||Ethanoic acid||Straight-chain fatty acid||2||1.16||0.87||Short|
|Trenbolone enanthatee||C17β||Heptanoic acid||Straight-chain fatty acid||7||1.41||0.71||Long|
|Footnotes: a = Length of ester in carbon atoms for straight-chain fatty acids or approximate length of ester in carbon atoms for aromatic fatty acids. b = Relative molecular weight compared to unesterified parent steroid. c = Relative anabolic steroid content by weight (i.e., relative androgenic potency) compared to unesterified parent steroid. d = Duration by intramuscular or subcutaneous injection. e = Never marketed. Sources: See individual articles.|