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Megestrol

Megestrol
Megestrol.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEBI
ECHA InfoCard100.020.571 Edit this at Wikidata
Chemical and physical data
FormulaC22H30O3
Molar mass342.472 g/mol
3D model (JSmol)
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Megestrol (INN, BAN) is a progestin of the 17α-hydroxyprogesterone group which was never marketed and is not currently used clinically.[1][2] Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.[1][2]

Synthesis

Megestrol synthesis:[3] U.S. Patent 2,891,079

See also

References

  1. ^ a b F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1267. ISBN 978-0-412-46630-4. Retrieved 12 May 2012.
  2. ^ a b Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 641. ISBN 978-3-88763-075-1. Retrieved 28 May 2012.
  3. ^ Ringold, H. J.; Ruelas, J. P.; Batres, E.; Djerassi, C. (1959). "Steroids. CXVIII.16-Methyl Derivatives of 17α-Hydroxyprogesterone and of Reichstein's Substance "S"". Journal of the American Chemical Society. 81 (14): 3712. doi:10.1021/ja01523a055.