While MAP can only be measured directly by invasive monitoring it can be approximately estimated using a formula in which the lower (diastolic) blood pressure is doubled and added to the higher (systolic) blood pressure and that composite sum then is divided by 3 to estimate MAP. In patients with sepsis, the vasopressor dosage may be titrated based on estimated MAP.
It is believed that a that is greater than 70 mmHg is enough to sustain the organs of the average person. is normally between 65 and 110 mmHg. MAP may be used similarly to Systolic blood pressure in monitoring and treating[clarification needed] for target blood pressure. Both have been shown advantageous targets for sepsis, trauma, stroke, intracranial bleed, and hypertensive emergencies.
If the falls below this number for an appreciable time, vital organs will not get enough oxygen perfusion, and will become hypoxic, a condition called ischemia.
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