Holbrook was coproprietor of the New Hygienic Institute at Laight Street in New York City, the property was previously Russell Trall's water-cure institution. A Turkish bath was located at the institute. He was a founder of Miller, Wood and Holbrook firm and Miller, Wood & Co publishers of medical books. He later published under his own name, M. L. Holbrook and was an important publisher of medical and hygienic literature up until the 1890s. The printing press was located at Laight Street in New York City. It shared the same address as Russell Trall's New York Hygeio-Therapeutic College.
Holbrook was an advocate of chastity. His 1894 book on the subject recommended a physical culture regimen to increase the body's strength and
diminish "morbid craving for unnatural and unreasonable indulgence of the passional nature." He was a prominent eugenicist and authored the 1897 book Stirpiculture, later re-printed as Homo-Culture.
The Herald of Health
From 1866, Holbrook was a long-term editor for Russell Trall's The Herald of Health (it became the Journal of Hygiene in 1893). He edited the journal until 1898. It was a very popular journal.
^ abcdefHoolihan, Christopher. (2001). An Annotated Catalogue of the Edward C. Atwater Collection of American Popular Medicine and Health Reform, Volume 1. University of Rochester Press. p. 460-465. ISBN1-58046-098-4