3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||411.48 g mol−1|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
L-694247 is a somewhat selective 5-HT1D agonist, with a 10-fold greater affinity for the 5-HT1B receptor, and 25-fold greater affinity for the 5-HT1A receptor. When L-694247 was injected intraventricularly in dehydrated rats, it inhibited water intake. Pre-treatment with a 5-HT1D antagonist abolished this effect. Administration of L-694,247 to normally hydrated rats had no effect on water intake.
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