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KCNC4

KCNC4
Protein KCNC4 PDB 1b4g.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKCNC4, C1orf30, HKSHIIIC, KSHIIIC, KV3.4, potassium voltage-gated channel subfamily C member 4
External IDsOMIM: 176265 MGI: 96670 HomoloGene: 68427 GeneCards: KCNC4
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for KCNC4
Genomic location for KCNC4
Band1p13.3Start110,211,343 bp[1]
End110,283,100 bp[1]
RNA expression pattern
PBB GE KCNC4 208251 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039574
NM_004978
NM_153763

NM_145922
NM_001356447

RefSeq (protein)

NP_001034663
NP_004969

NP_666034
NP_001343376

Location (UCSC)Chr 1: 110.21 – 110.28 MbChr 3: 107.44 – 107.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.[5]

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116396 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027895 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: KCNC4 potassium voltage-gated channel, Shaw-related subfamily, member 4".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.