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JWH-057

JWH-057
JWH-057.svg
Identifiers
CAS Number
ChemSpider
Chemical and physical data
FormulaC25H38O
Molar mass354.578 g·mol−1
3D model (JSmol)

JWH-057, also known as deoxy-Δ8-THC-DMH, is a selective cannabinoid ligand, with a binding affinity of Ki = 2.9 ± 1.6 nM for the CB2 subtype, and Ki = 23 ± 7 nM for CB1.[1]

See also

References

  1. ^ Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH (1996). "Synthesis and Pharmacology of a Very Potent Cannabinoid Lacking a Phenolic Hydroxyl with High Affinity for the CB2 Receptor". J. Med. Chem. 39 (20): 3875–3877. doi:10.1021/JM960394Y. PMID 8831752.