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Isopropamide

Isopropamide
Isopropamide.png
Clinical data
MedlinePlusa694006
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • US: ℞-only and Unscheduled
  • In general: unscheduled
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.028.470 Edit this at Wikidata
Chemical and physical data
FormulaC23H33N2O+
Molar mass353.52092 g/mol g·mol−1
3D model (JSmol)
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Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.

References

  • Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
  • Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.