Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over-the-counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.
Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.