This page uses content from Wikipedia and is licensed under CC BY-SA.

Gliquidone

Gliquidone
Gliquidone.svg
Clinical data
Trade namesGlurenorm
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • C
Routes of
administration
Oral (tablets)
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityHigh (Tmax = 2–3 hours)
MetabolismExtensive hepatic
Onset of action1–1.5 hours
ExcretionBiliary (95%), renal (5%)
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.046.770 Edit this at Wikidata
Chemical and physical data
FormulaC27H33N3O6S
Molar mass527.634 g/mol g·mol−1
3D model (JSmol)
  (verify)

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class. It is classified as a second-generation sulfonylurea. It is used in the treatment of diabetes mellitus type 2. It is marketed by the pharmaceutical company Boehringer Ingelheim (Germany).

Contraindications

Pharmacokinetics

Gliquidone is fully metabolized by the liver. Its metabolites are excreted virtually completely with bile (even with long-term administration), thus allowing the use of medication in diabetic patients suffering from kidney disease and diabetic nephropathy.[1]

References

  1. ^ a b "Glurenorm (gliquidone) 30 mg Tablets, for Oral Use. Full Prescribing Information". Russian State Register of Medicinal Products (in Russian). Boehringer Ingelheim. Retrieved 12 July 2016.