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Glia maturation factor

glia maturation factor, beta
Identifiers
SymbolGMFB
NCBI gene2764
HGNC4373
OMIM601713
RefSeqNM_004124
UniProtP60983
Other data
LocusChr. 14 q22.1
glia maturation factor, gamma
Identifiers
SymbolGMFG
NCBI gene9535
HGNC4374
OMIM604104
RefSeqNM_004877
UniProtO60234
Other data
LocusChr. 19 q13.2

Glia maturation factor is a neurotrophic factor implicated in nervous system development, angiogenesis and immune function. In humans, the glia maturation factor beta and glia maturation factor gamma proteins are encoded by the GMFB and GMFG genes, respectively.

The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains and suggest new means of experimentally addressing the function of this protein family.[1]

References

  1. ^ "Protein Summary". Retrieved 2008-10-31.

See also

Stereo ribbon diagram of the crystal structure of GMFG. Spectral coloring is from blue (N-terminus) to red (C-terminus). Secondary structural elements are indicated