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AliasesGPR139, GPRg1, PGR3, G protein-coupled receptor 139
External IDsOMIM: 618448 MGI: 2685341 HomoloGene: 45860 GeneCards: GPR139
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for GPR139
Genomic location for GPR139
Band16p12.3Start20,031,485 bp[1]
End20,073,917 bp[1]
RNA expression pattern
PBB GE GPR139 gnf1h10318 s at fs.png

PBB GE GPR139 gnf1h08229 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 16: 20.03 – 20.07 MbChr 7: 119.14 – 119.18 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 139 is a protein that in humans is encoded by the GPR139 gene.[5][6]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180269 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066197 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
  6. ^ "Entrez Gene: GPR139 G protein-coupled receptor 139".

Biochem Biophys Res Commun. 2003 May 23;305(1):67-71. Novel human G-protein-coupled receptors. Vanti WB1, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF.

Further reading

  • Ottolenghi C, Fellous M, Barbieri M, McElreavey K (2002). "Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination". Genomics. 79 (3): 333–43. doi:10.1006/geno.2002.6711. PMID 11863363.
  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
  • Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.
  • Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.