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GJA3

GJA3
Identifiers
AliasesGJA3, CTRCT14, CX46, CZP3, gap junction protein alpha 3
External IDsOMIM: 121015 MGI: 95714 HomoloGene: 9670 GeneCards: GJA3
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for GJA3
Genomic location for GJA3
Band13q12.11Start20,138,255 bp[1]
End20,161,052 bp[1]
RNA expression pattern
PBB GE GJA3 208590 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021954

NM_001271623
NM_016975

RefSeq (protein)

NP_068773

NP_001258552
NP_058671

Location (UCSC)Chr 13: 20.14 – 20.16 MbChr 14: 57.03 – 57.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction alpha-3 protein is a protein that in humans is encoded by the GJA3 gene.[5][6][7]

Interactions

GJA3 has been shown to interact with Tight junction protein 1.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000121743 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048582 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Mackay D, Ionides A, Kibar Z, Rouleau G, Berry V, Moore A, Shiels A, Bhattacharya S (May 1999). "Connexin46 mutations in autosomal dominant congenital cataract". Am J Hum Genet. 64 (5): 1357–64. doi:10.1086/302383. PMC 1377871. PMID 10205266.
  6. ^ Rosenberg AM, Gole GA (Jul 1982). "Morning Glory Syndrome: a report of two cases". Aust J Ophthalmol. 9 (4): 263–5. doi:10.1111/j.1442-9071.1981.tb00919.x. PMID 7342922.
  7. ^ "Entrez Gene: GJA3 gap junction protein, alpha 3, 46kDa".
  8. ^ Nielsen, Peter A; Baruch Amos; Shestopalov Valery I; Giepmans Ben N G; Dunia Irene; Benedetti E Lucio; Kumar Nalin M (Jun 2003). "Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1)". Mol. Biol. Cell. 14 (6): 2470–81. doi:10.1091/mbc.E02-10-0637. ISSN 1059-1524. PMC 194895. PMID 12808044.

Further reading