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GABA receptor antagonist

GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used for counteracting overdoses of sedative drugs.

Examples include bicuculline, securinine and metrazol, and the benzodiazepine GABAA receptor antagonist flumazenil.

Also the antibiotic ciprofloxacin, thujone, ginkgo biloba, kudzu and muira puama[citation needed] may have properties of GABAA receptor antagonism.

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