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Fluorolintane structure.png
Legal status
Legal status
Chemical and physical data
Molar mass269.363 g·mol−1
3D model (JSmol)

Fluorolintane (also known as 2-FPPP) is a dissociative anesthetic drug that has been sold online as a designer drug.[1][2]

Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[3] and have been studied in vitro as potential treatments for neurotoxic injury,[4] depression[5] and as sympathomimetic.[6]

See also


  1. ^ Wallach J, Kavanagh PV, McLaughlin G, Morris N, Power JD, Elliott SP, et al. (May 2015). "Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers" (PDF). Drug Testing and Analysis. 7 (5): 358–67. doi:10.1002/dta.1689. PMID 25044512.
  2. ^ "Analytical Report - Fluorolintane" (PDF). Nacionalni forenzični laboratorij (NFL). January 2016.
  3. ^ Berger ML, Schweifer A, Rebernik P, Hammerschmidt F (May 2009). "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry. 17 (9): 3456–62. doi:10.1016/j.bmc.2009.03.025. PMID 19345586.
  4. ^ Gray NM, Cheng BK. "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". Retrieved 17 June 2015.
  5. ^ Aspergren BD, Heinzelman RV (1963). "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". Retrieved 22 June 2015.
  6. ^ Heinzelman RV, Aspergren BD (July 1953). "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemical Society. 75 (14): 3409–3413. doi:10.1021/ja01110a033.