|AHFS/Drugs.com||International Drug Names|
|Elimination half-life||~3 h|
|Excretion||50% urine, 36% feces|
|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||281.234 g·mol−1|
|3D model (JSmol)|
|Melting point||124 to 125 °C (255 to 257 °F) resolidification and remelting at 134°C to 136°C|
|Solubility in water||Practically insoluble in water; soluble in ethanol, chloroform and diethyl ether mg/mL (20 °C)|
Flufenamic acid (FFA) is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs:718 Like other members of the class, it is a COX inhibitor and prevents formation of prostaglandins. FFA is known to bind to and reduce the activity of prostaglandin F synthase and activate TRPC6.
It is not widely used in humans as it has a high rate (30-60%) of gastrointestinal side effects.:310 It is generally not available in the US. It is available in some Asian and European countries as a generic.
|Pyrazolones / |
|Acetic acid derivatives|
and related substances
|Propionic acid derivatives|
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