The order Flavobacteriales is of one of the four orders from the phylum Bacteroidetes. Comparative genomic studies have identified several conserved indels, as well as 27 proteins that are uniquely shared by different sequenced Flavobacteriales and Bacteroidetes species supporting this inference. Additionally, these studies have also identified 38 proteins that seem to be specific for the species from the order Flavobacteriales. Of these proteins, 26 were present in all sequenced species, while the remaining 12 were missing in only one or two species. These signature proteins provide potential molecular markers for this order. Several proteins have also been identified which are unique to the Flavobacteriales and Bacteroidales orders, indicating the species from these two orders shared a common ancestor exclusive of other Bacteroidetes.
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