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Clinical data
Trade namesOvalyse
Other namesTAP-031; U-69689; 9-(N-Ethyl-L-prolinamide)-10-deglycinamide; 9-(N)-Et-ProNH2-10-des-GlyNH2-LHRH; Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-NHEt
Drug classGnRH analogue; GnRH agonist; Antigonadotropin
ATCvet code
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.164.570 Edit this at Wikidata
Chemical and physical data
Molar mass1153.313 g/mol g·mol−1
3D model (JSmol)

Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist) which has been marketed in the United Kingdom and Austria.[1][2][3] It may no longer be available.[4] Fertirelin has been used in veterinary medicine.[2] It may have been used in the treatment of sex hormone-dependent conditions and infertility in women.[3] The drug was first introduced in 1981 in Japan to treat various kinds of ovarian failure in cattle.[5] Fertirelin is a synthetic peptide and GnRH analogue.[1][2] It is used as the acetate salt.[2]

See also


  1. ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 549–. ISBN 978-1-4757-2085-3.
  2. ^ a b c d Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 441–. ISBN 978-3-88763-075-1.
  3. ^ a b I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 120–. ISBN 978-94-011-4439-1.
  4. ^ []
  5. ^ Okada J, Seo T, Kasahara F, Takeda K, Kondo S (1991). "New degradation product of des-Gly10-NH2-LH-RH-ethylamide (fertirelin) in aqueous solution". J Pharm Sci. 80 (2): 167–70. doi:10.1002/jps.2600800217. PMID 2051323.