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Estradiol valerate/cyproterone acetate

Estradiol valerate /
cyproterone acetate
Estradiol valerate.svg
Cyproterone acetate.svg
Combination of
Estradiol valerateEstrogen
Cyproterone acetateProgestogen
Clinical data
Trade namesClimen, Femilar
Routes of
By mouth
Drug classEstrogen; Progestogen
Legal status
Legal status

Estradiol valerate/cyproterone acetate (EV/CPA), sold under the brand names Climen and Femilar among others, is a combination product of estradiol valerate, an estrogen, and cyproterone acetate, a progestogen, which is used in menopausal hormone therapy in and as a birth control pill to prevent pregnancy in women.[1] It is taken by mouth.[1]

See also


  1. ^ a b Hirvonen E, Stenman UH, Mälkönen M, Rasi V, Vartiainen E, Ylöstalo P (October 1988). "New natural oestradiol/cyproterone acetate oral contraceptive for pre-menopausal women". Maturitas. 10 (3): 201–13. doi:10.1016/0378-5122(88)90023-0. PMID 2972897.