Entandrophragma is restricted to tropical Africa. At least some of the species attain large sizes, reaching 40–50 m tall, exceptionally 60 m, and 2 m in trunk diameter. In 2016 a specimen of Entandrophragma excelsum towering more than 80 m was identified at Kilimanjaro.
The leaves are pinnate, with 5-9 pairs of leaflets, each leaflet 8–10 cm long with an acuminate tip. The flowers are produced in loose inflorescences, each flower small, with five yellowish petals about 2 mm long, and ten stamens. The fruit is a five-valved capsule containing numerous winged seeds.
The timber of a few species is traded as a tropical hardwood. It is sometimes termed under the generic label of mahogany, and while Entandrophragma is part of the family Meliaceae, it is not classified as genuine mahogany. The species shares many of the characteristics of genuine mahogany and is used as an alternative, with Sapele and Utile in particular bearing a close resemblance.