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EMPA (drug)

EMPA
EMPA.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
ECHA InfoCard100.233.393 Edit this at Wikidata
Chemical and physical data
FormulaC23H26N4O4S
Molar mass454.542 g/mol g·mol−1
3D model (JSmol)

EMPA is a selective antagonist of the OX2 receptor, with 900-fold selectivity in binding for OX2 over OX1.[1][2]

See also

References

  1. ^ Malherbe, P; Borroni, E; Pinard, E; Wettstein, JG; Knoflach, F (2009). "Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists". Mol Pharmacol. 76 (3): 618–31. doi:10.1124/mol.109.055152. PMID 19542319.
  2. ^ Malherbe; et al. (2009). "Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX2 receptor". Br. J. Pharmacol. 156 (8): 1326–41. doi:10.1111/j.1476-5381.2009.00127.x. PMC 2697736. PMID 19751316.