Edward Donnall "Don" Thomas (March 15, 1920 – October 20, 2012) was an American  physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia.
Mart, Texas, Thomas often shadowed his father who was a general practice doctor.
Later, he attended the University of Texas at Austin where he studied chemistry and chemical engineering, graduating with a B.A. in 1941 and an M. A. in 1943. While Thomas was an undergraduate he met his wife, Dorothy (Dottie) Martin while she was training to be journalist. They had three children. Thomas entered Harvard Medical School in 1943, receiving an M.D. in 1946. Dottie became a lab technician during this time to support the family, and the pair worked closely thereafter. He did his residency at Peter Bent Brigham Hospital before joining the US Army. "In 1955, he was appointed physician in chief at the Mary Imogene Bassett Hospital, now Bassett Medical Center, in Cooperstown, N.Y., an affiliate of Columbia University."
At Mary Imogene Bassett, he began to study rodents that received lethal doses of radiation who were then saved by an infusion of marrow cells. At the time, patients who underwent bone marrow transplantation all died from infections or immune reactions that weren't seen in the
rodent studies. Thomas began to use dogs as a model system. In 1963, he moved his lab to the United States Public Health Service in Seattle.
Thomas also received
National Medal of Science in 1990. In 2003 he was one of 22 Nobel laureates who signed the Humanist Manifesto.
He died of heart failure and is survived by his three children.
His wife Dottie died in 2015 aged 92.
Awards and honors
1965-1969 Hematology Study Section, National Institutes of Health
1969-1973 Member, Board of Trustees and Medical and Scientific Advisory Committee, Leukemia Society of America, Inc.
1970-1974 Clinical Cancer Investigation Review Committee, National Cancer Institute
1974 First Annual Eugene C. Eppinger Lecture at Peter Bent Brigham Hospital and the Harvard Medical School
1975 A. Ross McIntyre Award, University of Nebraska Medical Center
1975 The Henry M. Stratton Lecture, American Society of Hematology, Dallas
1977 The Lilly Lecture, Royal College of Physicians, London
1979 The Philip Levine Award, American Society of Clinical Pathologists, New Orleans
1980 American Cancer Society Award for Distinguished Service in Basic Research
Kettering Prize of the General Motors Cancer Research Foundation for contributions to the diagnosis and treatment of cancer 1981 Honorary Doctorate of Medicine, University of Cagliari, Sardinia
1981 Special Keynote Address Award, American Society of Therapeutic Radiologists
1982 Stratton Lecture, International Society of Hematology
1982 Paul Aggeler Lecturer, University of California, San Francisco
1983 David A. Karnofsky Memorial Lecturer, Annual Meeting of the American Society of Clinical Oncology
1983 Robert Roesler de Villiers Award, Leukemia Society of American
1984 Sixty-fifth Mellon Lecturer, University of Pittsburgh School of Medicine, May 13
1985 Stanley Wright Memorial Lecturer, Annual Meeting of the Western Society for Pediatric Research
Karl Landsteiner Memorial Award, Annual Meeting of the American Association of Blood Banks, 1987-1988 President, American Society of Hematology
1989 Elected Corresponding Member, Academie Royale de Medecine de Belgigue
1990 Terry Fox Award, Canada
Gairdner Foundation International Award 1990 North American Medical Association of Hong Kong Prize
1990 Nobel Prize in Medicine
1990 Presidential Medal of Science
1991 Adolfo Ferrata Lecture, Italian Society of Hematology, Verona, Italy
1991 Honorary Doctorate of Medicine, University of Verona
1992 Kober Medal, American Association of Physicians
1992 Honorary Member, The Royal College of Physicians and Surgeons of Canada
1992 Honorary Doctorate of Medicine, University of Parma
1994 Honorary Member, National Academia of Medicine
1994 Honorary Degree, University of Barcelona
1996 Honorary Degree, University of Warsaw
1998 Medal of Merit, State of Washington
^ Frederick R. Appelbaum.
Perspective: E. Donnall Thomas (1920–2012) Science 338(6111):1163, 30 November 2012
Park, B; Yoo, KH; Kim, C (December 2015). "Hematopoietic stem cell expansion and generation: the ways to make a breakthrough". Blood Research. 50 (4): 194–203. doi: 10.5045/br.2015.50.4.194. PMC . 4705045 PMID 26770947. Dr. Donnall Thomas, who received Nobel Prize for his pioneering work in bone marrow transplantation to cure leukemia and other hematologic malignancies, must be recognized and apprised as human endeavor to cure previously incurable diseases.
"E. Donnall Thomas, Who Advanced Bone Marrow Transplants, Dies at 92". The New York Times. October 24, 2012.
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Storb, R. (2012). "Edward Donnall Thomas (1920–2012)". Nature. 491 (7424): 334. Bibcode: 2012Natur.491..334S. doi: . 10.1038/491334a PMID 23151572.
"Notable Signers". Humanism and Its Aspirations. American Humanist Association . Retrieved . October 4, 2012