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DNQX

DNQX
Skeletal formula
Space-filling model of DNQX
Names
IUPAC name
6,7-Dinitroquinoxaline-2,3(1H,4H)-dione
Identifiers
3D model (JSmol)
ChemSpider
DrugBank
UNII
Properties
C8H4N4O6
Molar mass 252.142 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

DNQX (6,7-dinitroquinoxaline-2,3-dione) is a competitive antagonist at AMPA and kainate receptors, two ionotropic glutamate receptor (iGluR) subfamilies.[1] It is used in a variety of molecular biology subfields, notably neurophysiology, to assist researchers in determining the properties of various types of ion channels and their potential applications in medicine.

See also

References

  1. ^ Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R (September 2010). "Glutamate receptor ion channels: structure, regulation, and function". Pharmacological Reviews. 62 (3): 405–96. doi:10.1124/pr.109.002451. PMC 2964903. PMID 20716669.

External links