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Chloride channel opener

A chloride channel opener is a type of drug which facilitates ion transmission through chloride channels.

An example is 1,10-phenanthroline, which activates Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels.[1]

GABA-A receptor agonists (e.g lorazepam) may also be considered chloride channel openers

See also

References

  1. ^ Duszyk M, MacVinish L, Cuthbert AW (October 2001). "Phenanthrolines--a new class of CFTR chloride channel openers". British Journal of Pharmacology. 134 (4): 853–64. doi:10.1038/sj.bjp.0704328. PMC 1573018. PMID 11606326.

Further reading