Cedars-Sinai focuses on biomedical research and technologically advanced medical education—based on an interdisciplinary collaboration between physicians and clinical researchers. The facility has research centers covering cardiovascular, genetics, gene therapy, gastroenterology, neuroscience, immunology, surgery, organ transplantation, stem cells, biomedical imaging and cancer—with more than 800 research projects underway (led by 230 principal investigators). The Graduate School of Biomedical Sciences at Cedars-Sinai offers a PhD Program in Biomedical Sciences and Masters degree programs in Magnetic Resonance in Medicine and Health Delivery Science.
Certified as a level I trauma center for adults and pediatrics, Cedars-Sinai trauma-related services range from prevention to rehabilitation and are provided in concert with the hospital's Department of Surgery. Cedars-Sinai is affiliated with the Keck School of Medicine at the University of Southern California (USC) and David Geffen School of Medicine at the University of California, Los Angeles (UCLA).
As of 2019, U.S. News & World Report ranked Cedars-Sinai #3 in the western United States, with number one being Ronald Reagan UCLA Medical Center. Cedars-Sinai also earned national rankings in 12 adult specialties including:
-Cancer (No. 12)
-Cardiology and Heart Surgery (No. 3)
-Diabetes and Endocrinology (No. 16)
-Ear, Nose and Throat (No. 38)
-Gastroenterology and GI Surgery (No. 2)
-Geriatrics (No. 12)
-Gynecology (No. 8)
-Nephrology (No. 10)
-Neurology and Neurosurgery (No. 12)
-Orthopaedics (No. 3)
-Pulmonology (No. 4)
-Urology (No. 12)
 Located in the Harvey Morse Auditorium, Cedars-Sinai's patient care is depicted in the Jewish Contributions to Medicine mural. The heart transplantation program at Cedars-Sinai Medical Center has experienced unprecedented growth since 2010.
Founded by businessman Kaspare Cohn, Cedars of Lebanon Hospital was established as the Kaspare Cohn Hospital in 1902. At the time, Cohn donated a two-story Victorian home at 1441 Carroll Avenue in the Angeleno Heights neighborhood of Los Angeles. The hospital had just 12 beds when it opened on September 21, 1902, and its services were initially free. From 1906 to 1910, Dr. Sarah Vasen, the first female doctor in Los Angeles, acted as superintendent. In 1910, the hospital relocated and expanded to Stephenson Avenue (now Whittier Boulevard), where it had 50 beds and a backhouse containing a 10-cot tubercular ward. It gradually transformed from a charity-based hospital to a general hospital and began to charge patients. In 1930, the hospital moved to 4833 Fountain Avenue, where it opened as Cedars of Lebanon Hospital, named after the religiously significant Lebanon Cedars tree (cedrus libani); which were highly sought after and used to build King Solomon's Temple in Jerusalem. Cedars of Lebanon Hospital could accommodate 279 patients and was large and comprehensive, with all of the components of a modern medical facility. For example, specific departments were instituted for general medicine, surgery, pediatrics, maternity, physical therapy, and other speciality departments.
Mount Sinai Hospital
Meanwhile in 1918, the Bikur Cholim Society opened a two-room hospice, the Bikur Cholim Hospice, when the Great Influenza Pandemic hit the United States of America. In 1921, the hospice relocated to an eight-bed facility in Boyle Heights and was renamed Bikur Cholim Hospital. On November 7, 1926, it was renamed Mount Sinai Hospital and moved to a 50-bed facility on Bonnie Beach Place in Los Angeles. Later, in 1950, a new Mount Sinai Hospital was built on land donated by Emma and Hyman Levine at 8700 Beverly Boulevard. They had purchased three-and-one-half acres of land and donated the property to Mount Sinai Hospital under the auspices of their foundation.
Merger of Cedars of Lebanon Hospital and Mount Sinai Hospital
On Tuesday Feb 7th, 1961, Cedars of Lebanon Hospital and Mt. Sinai announced plans for the establishment of a unified medical center of 1,000 beds or more.
Cedars of Lebanon Hospital and Mount Sinai Hospital merged in 1961 to form Cedars-Sinai Medical Center. The unification of the two hospitals was one of the most significant consolidations ever achieved by hospitals; it was in response to community needs for improved and extend health services made necessary by population growth and by modern medical progress. Donations in the amount of 4 million dollars from the Max Factor Family Foundation allowed the construction of the main hospital building, which broke ground on November 5, 1972, and opened on April 3, 1976.
In 1994, the Cedars-Sinai Health System was established, comprising the Cedars-Sinai Medical Care Foundation, the Burns and Allen Research Institute and Cedars-Sinai Medical Center. The Burns and Allen Research Institute, named for George Burns and his wife, Gracie Allen, is located inside the Barbara and Marvin Davis Research Building. Opened in 1996, it houses biomedical research aimed at discovering genetic, molecular and immunological factors that trigger disease.
In 2006, Cedars-Sinai added the Saperstein Critical Care Tower with 150 ICU beds.
In 2008[update], Cedars-Sinai served 54,947 inpatients and 350,405 outpatients, and there were 77,964 visits to the emergency room. Cedars-Sinai received high rankings in 11 of the 16 specialties, ranking in the top 10 for digestive disorders and in the top 25 for five other specialties as listed below.
In 2013, Cedars-Sinai opened its 800,000-square-foot Advanced Health Sciences Pavilion, which consists of eight stories of program space located over a six-story parking structure, on the eastern edge of its campus at the corner of San Vicente Boulevard and Gracie Allen Drive. Designed by architectural firm HOK, the Pavilion brings patient care and translational research together in one site. The Advanced Health Sciences Pavilion houses the Cedars-Sinai's neurosciences programs, the Cedars-Sinai Heart Institute and Regenerative Medicine Institute laboratories, as well as outpatient surgery suites, an imaging area and an education center.
Cedars-Sinai ranked as follows in the nationwide U.S. News Best Hospitals 2019–20 report:
Worth Magazine selected Cedars-Sinai Smidt Heart Institute as one of the United States' Top 25 Hospitals for Cardiac Bypass Surgery.
Cedars-Sinai's Gynecologic Oncology Division was named among the nation's Top 10 Clinical Centers of Excellence by Contemporary OB/GYN in 2009.
Cedars-Sinai is one of the leading institutes for competitive research funding from the National Institutes of Health. As an international leader in biomedical research, it translates discoveries into successful treatments with global impact. Cedars-Sinai investigators pair basic scientific research in areas of stem cell biology, immunology, neuroscience and genetics, with clinical and translational discoveries, to continue advancing medical breakthroughs. Total research expenditure in 2018-19 was $227 million. In fiscal year 2019, Cedars-Sinai received $70 million in funding from the National Institutes of Health.
Some notable research areas and organized research units at Cedars-Sinai are:
Artificial Intelligence in Medicine
Biostatistics and Bioinformatics Research Center
Center for Bioinformatics and Functional Genomics
Center for Cardiac Arrest Prevention
Center for Integrated Research in Cancer and Lifestyle
Center for Neural Science and Medicine
Center for Outcomes Research and Education
Diabetes and Obesity Research
Digestive Diseases Research
Division of Informatics
Genetics and Genomics Research
Immunology and Infectious Diseases Research
Medically Associated Science and Technology
Regenerative Medicine Research
Women's Health Research
Keith Black, department chair of Neurosurgery and director of the Maxine Dunitz Neurosurgical Institute, has successfully performed over 4,000 brain surgeries and has made significant medical advances relating to neurosurgery.
Bruce Gewertz, Surgeon-in-Chief, Chair of the Department of Surgery, Vice-Dean for Academic Affairs and Vice-president for Interventional Services.
David Ho was a resident at Cedars-Sinai when he encountered some of the first cases of what was later labeled AIDS.
David Rimoin, chair of Pediatrics for 18 years, specialized in genetics and was a pioneer researcher in dwarfism and skeletal dysplasia. Together with Michael Kaback, discovered the enzyme screening for Tay Sachs disease, reducing incidences of the deadly disease by 90 percent.
February 18, 2013: Owner of the Los Angeles LakersJerry Buss died at age 80 after having been hospitalized with an undisclosed form of cancer. His immediate cause of death was listed as kidney failure.
November 12, 2018: Marvel Comic-book writer Stan Lee died after he had been rushed to the hospital that morning.
April 29, 2019: In a notice from his family following his death from a stroke, it was stated that John Singleton had been taken there and treated for a stroke, and that he had been removed from life support after having fallen into a coma earlier due to the stroke. His death was confirmed hours after being removed from life support.
Mark Wahlberg and Rhea Durham's eldest daughter, Ella Rae on September 2, 2003, oldest son, Michael on March 21, 2006, youngest son, Brendan Joseph on September 16, 2008, and youngest daughter, Grace Margaret on January 11, 2010.
Kate Hudson's eldest son, Ryder Russell Robinson on January 7, 2004 (with ex-husband Chris Robinson), youngest son, Bingham Hawn Bellamy on July 9, 2011 (with ex-fiancé Matt Bellamy), and daughter, Rani Rose Hudson Fujikawa on October 2, 2018 (with boyfriend Danny Fujikawa).
Julia Roberts and Daniel Moder's twins, Hazel Patricia and Phinnaeus Walter on November 28, 2004 and youngest son, Henry Daniel on June 18, 2007.
Tori Spelling and Dean McDermott's eldest son, Liam Aaron on March 13, 2007, oldest daughter, Stella Doreen on June 9, 2008, youngest daughter, Hattie Margaret on October 10, 2011, second son, Finn Davey on August 30, 2012, and youngest son, Beau Dean on March 2, 2017.
Daisy Eagan’s son, Monty Harrison Eagan-Bloom, May 11, 2013 (with boyfriend Kurt Bloom).
Kim Kardashian and Kanye West's eldest daughter, North West on June 15, 2013, oldest son, Saint West on December 5, 2015, youngest daughter, Chicago West (via a surrogate) on January 15, 2018, and youngest son, Psalm West (via a surrogate) on May 9, 2019.
According to articles in the Los Angeles Times in 2009, Cedars-Sinai was under investigation for significant radiation overdoses of 206 patients during CT brain perfusion scans during an 18-month period. Since the initial investigation, it was found that GE sold several products to various medical centers with faulty radiation monitoring devices.
In 2011, Cedars-Sinai again created controversy by denying a liver transplant to medical marijuana patient Norman Smith. They removed Mr. Smith from a transplant waiting list for "non-compliance of our substance abuse contract", despite his own oncologist at Cedars-Sinai having recommended that he use the marijuana for his pain and chemotherapy. Dr. Steven D. Colquhoun, director of the Liver Transplant Program, said that the hospital "must consider issues of substance abuse seriously", but the transplant center did not seriously consider whether Mr. Smith was "using" marijuana versus "abusing" it. In 2012, Cedars-Sinai denied a liver transplant to a second patient, Toni Trujillo, after her Cedars-Sinai doctors knew and approved of her legal use of medical marijuana. In both cases, the patients acceded to the hospital's demand and stopped using medical marijuana, despite its therapeutic benefits for them, but were both sent six years back to the bottom of the transplant list. His death inspired Americans for Safe Access to lobby for the California Medical Cannabis Organ Transplant Act (AB 258), which was enacted in July 2015 to protect future patients from dying at the hands of medical establishments prejudiced against the legal use of medical cannabis.
Patient data security breaches
On June 23, 2014, an unencrypted employee laptop was stolen from an employee's home. The laptop contained patient Social Security numbers and patient health data. On June 18 through June 24, 2013, six employees were terminated for inappropriately accessing 14 patient records around the time Kim Kardashian and Kanye West's daughter was born at the hospital.
^"Fanny Brice Dies at the Age of 59". The New York Times. May 30, 1951. Retrieved 2014-10-26. Fanny Brice, stage and screen comedienne and the Baby Snooks of radio, died at 11:15 A. M. today at the Cedars of Lebanon Hospital. Her age was 59. Miss Brice suffered a massive cerebral hemorrhage last Thursday morning and was rushed to the hospital from her home in Beverly Hills. She never again regained consciousness, although she was placed in an oxygen tent. ...
^Cedars-Sinai investigated for significant radiation overdoses of 206 patients, Alan Zarembo, Los Angeles Times, October 10, 2009; "4 patients say Cedars-Sinai did not tell them they had received a radiation overdose", Alan Zarembo, Los Angeles Times, October 15, 2009; Cedars-Sinai finds more patients exposed to excess radiation, Nicole Santa Cruz, Los Angeles Times, November 9, 2009;