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Cantuzumab ravtansine

Cantuzumab ravtansine
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetMUC1
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
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KEGG
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Cantuzumab ravtansine (huC242-SPDB-DM4) is an antibody-drug conjugate designed for the treatment of cancers. The humanized monoclonal antibody cantuzumab (huC242) is linked to a cytotoxic agent, ravtansine (DM4).[1] It uses a more hindered disulfide linkage than cantuzumab mertansine.[2]

See also

References

  1. ^ World Health Organization (2011). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 105" (PDF). WHO Drug Information. 25 (2).
  2. ^ Antibody-Drug Conjugates and Immunotoxins: From Pre-Clinical Development to ...