ECHA InfoCard 100.236.929
C 21 H 30 O 2
g·mol 314.469 −1
Except where otherwise noted, data are given for materials in their
(at 25 °C [77 °F], 100 kPa).
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Cannabichromene (CBC), also called cannabichrome, cannanbichromene, pentylcannabichromene or cannabinochromene, is one of the hundreds of  cannabinoids found in the plant, Cannabis and is therefore a  phytocannabinoid. It bears structural similarity to the other natural cannabinoids, including tetrahydrocannabinol (THC), tetrahydrocannabivarin (THCV), cannabidiol (CBD), and cannabinol (CBN), among others.  CBC and its derivatives are as abundant as  cannabinols in cannabis. It is not scheduled by the  Convention on Psychotropic Substances.
plant, CBC occurs mainly as cannabichromenic acid (CBCA, 2-COOH-CBC, CBC-COOH). Cannabis Geranyl pyrophosphate and olivetolic acid combine to produce cannabigerolic acid (CBGA; the sole intermediate for all other phytocannabinoids), which is cyclized by the enzyme CBCA synthase to form CBCA. Over time, or when heated above 200° F, CBCA is decarboxylated, producing CBC. See also the biosynthetic scheme image below.
CBC biosynthetic scheme
As of 2017, CBC is under laboratory research to identify its possible
pharmacological properties. No in vivo human studies exist as of 2019.     In vitro, CBC is not active at CB1 or CB2 receptors, but is an agonist of TRPA1 and less potently, an agonist of TRPV3 and TRPV4. CBC has two  stereoisomers.
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