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Protein COPG PDB 1pzd.png
Available structures
PDBOrtholog search: PDBe RCSB
AliasesCOPG1, COPG, coatomer protein complex subunit gamma 1, COPI coat complex subunit gamma 1
External IDsOMIM: 615525 MGI: 1858696 HomoloGene: 56745 GeneCards: COPG1
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for COPG1
Genomic location for COPG1
Band3q21.3Start129,249,606 bp[1]
End129,277,773 bp[1]
RNA expression pattern
PBB GE COPG 217749 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 3: 129.25 – 129.28 MbChr 6: 87.89 – 87.91 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene.[5][6] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.[5]


COPG has been shown to interact with Dopamine receptor D1,[7] COPZ1[5][8] and COPB1.[5][9]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181789 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030058 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b c d Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
  6. ^ "Entrez Gene: COPG coatomer protein complex, subunit gamma".
  7. ^ Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. Germany. 81 (2): 77–85. doi:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085.
  8. ^ Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. UNITED STATES. 135 (1): 53–61. doi:10.1083/jcb.135.1.53. ISSN 0021-9525. PMC 2121028. PMID 8858162.
  9. ^ Lowe, M; Kreis T E (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. UNITED STATES. 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. ISSN 0021-9258. PMID 8940050.

External links

Further reading