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CLIC2

CLIC2
Protein CLIC2 PDB 2PER.png
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesCLIC2, CLIC2b, MRXS32, XAP121, chloride intracellular channel 2, CLCNL2
External IDsOMIM: 300138 HomoloGene: 48010 GeneCards: CLIC2
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for CLIC2
Genomic location for CLIC2
BandXq28Start155,276,211 bp[1]
End155,334,657 bp[1]
RNA expression pattern
PBB GE CLIC2 213415 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289

n/a

RefSeq (protein)

NP_001280

n/a

Location (UCSC)Chr X: 155.28 – 155.33 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene.[3][4]

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 2 is a member of the p64 family; the protein is detected in fetal liver and adult skeletal muscle tissue. This gene maps to the candidate region on chromosome X for incontinentia pigmenti.[4]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000155962 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Heiss NS, Poustka A (Nov 1997). "Genomic structure of a novel chloride channel gene, CLIC2, in Xq28". Genomics. 45 (1): 224–8. doi:10.1006/geno.1997.4922. PMID 9339381.
  4. ^ a b "Entrez Gene: CLIC2 chloride intracellular channel 2".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.