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AliasesCACNG4, calcium voltage-gated channel auxiliary subunit gamma 4
External IDsOMIM: 606404 MGI: 1859167 HomoloGene: 8674 GeneCards: CACNG4
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for CACNG4
Genomic location for CACNG4
Band17q24.2Start66,964,707 bp[1]
End67,033,398 bp[1]
RNA expression pattern
PBB GE CACNG4 62987 r at fs.png

PBB GE CACNG4 221585 at fs.png

PBB GE CACNG4 gnf1h00164 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 17: 66.96 – 67.03 MbChr 11: 107.73 – 107.79 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene.[5][6]

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes.[6]

See also


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000075461 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020723 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Burgess DL, Davis CF, Gefrides LA, Noebels JL (Jan 2000). "Identification of Three Novel Ca2+ Channel γ Subunit Genes Reveals Molecular Diversification by Tandem and Chromosome Duplication". Genome Res. 9 (12): 1204–13. doi:10.1101/gr.9.12.1204. PMC 311002. PMID 10613843.
  6. ^ a b "Entrez Gene: CACNG4 calcium channel, voltage-dependent, gamma subunit 4".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.