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Butaclamol

Butaclamol
Butaclamol.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H31NO
Molar mass361.52 g/mol g·mol−1
3D model (JSmol)

Butaclamol (AY-23,028) is a typical antipsychotic which was never marketed.[1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist.[2]

Chemistry

pKa = 7.15 (uncorrected for ionic strength)[3]

References

  1. ^ Buckingham, J (1985). Dictionary of organic compounds - Google Books. ISBN 9780412540905.
  2. ^ [www.sigmaaldrich.com]
  3. ^ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.