Bunyamwera virus ( BUNV) is a negative-sense, single-stranded enveloped RNA virus. It is the type species of the Orthobunyavirus genus, in the Bunyavirales order.
Bunyamwera virus can infect both humans and
(yellow fever mosquito). Aedes aegypti
It is named for Bunyamwera, a town in western
Uganda, where the type species was isolated in 1943. Reassortant viruses derived from Bunyamwera virus, such as Ngari virus, which has been associated with large outbreaks of viral haemorrhagic fever in Kenya and Somalia.  
The genetic structure of
Bunyamwera virus is typical for viruses, which are a family of enveloped Bunyavirales negative-sense, single-stranded RNA viruses with a genome split into three parts—Small (S), Middle (M), and Large (L). The L RNA segment encodes an RNA-dependent RNA polymerase (L protein), the M RNA segment encodes two surface glycoproteins (Gc and Gn) and a nonstructural protein (NSm), while the S RNA segment encodes a nucleocapsid protein (N) and, in an alternative overlapping reading frame, a second nonstructural protein (NSs). The genomic RNA segments are encapsidated by copies of the N protein in the form of  ribonucleoprotein (RNP) complexes. The N protein is the most abundant protein in virus particles and infected cells and, therefore, the main target in many serological and molecular diagnostics.  
Disease in humans
Bunyamwera virus causes Bunyamwera fever.
Gerrard SR, Li L, Barrett AD, Nichol ST (2004). "Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa". J Virol. 78 (16): 8922–6. doi: 10.1128/JVI.78.16.8922-8926.2004. PMC . 479050 PMID 15280501.
Odhiambo C, Venter M, Limbaso K, Swanepoel R, Sang R (2014). "Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from northern Kenya". PLOS ONE. 9 (8): e105446. Bibcode: 2014PLoSO...9j5446O. doi: 10.1371/journal.pone.0105446. PMC . 4143288 PMID 25153316.
Briese, T.; Bird, B.; Kapoor, V.; Nichol, S. T.; Lipkin, W. I. (12 May 2006). "Batai and Ngari Viruses: M Segment Reassortment and Association with Severe Febrile Disease Outbreaks in East Africa". Journal of Virology. 80 (11): 5627–5630. doi: 10.1128/JVI.02448-05. PMC . 1472162 PMID 16699043.
Plyusnin, Alexander; Elliott, Richard M (2011-01-01). . Norfolk, UK: Caister Academic Press. Bunyaviridae: molecular and cellular biology ISBN 9781904455905.
Ariza, Antonio; Tanner, Sian J.; Walter, Cheryl T.; Dent, Kyle C.; Shepherd, Dale A.; Wu, Weining; Matthews, Susan V.; Hiscox, Julian A.; Green, Todd J. (2013-06-01). "Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization". Nucleic Acids Research. 41 (11): 5912–5926. doi: 10.1093/nar/gkt268. ISSN 0305-1048. PMC . 3675483 PMID 23595147.
Bilk, S.; Schulze, C.; Fischer, M.; Beer, M.; Hlinak, A.; Hoffmann, B. (2012-09-14). "Organ distribution of Schmallenberg virus RNA in malformed newborns". Veterinary Microbiology. 159 (1–2): 236–238. doi: 10.1016/j.vetmic.2012.03.035.
Bréard, Emmanuel; Lara, Estelle; Comtet, Loïc; Viarouge, Cyril; Doceul, Virginie; Desprat, Alexandra; Vitour, Damien; Pozzi, Nathalie; Cay, Ann Brigitte (2013-01-15). "Validation of a Commercially Available Indirect Elisa Using a Nucleocapside Recombinant Protein for Detection of Schmallenberg Virus Antibodies". PLOS ONE. 8 (1): e53446. Bibcode: 2013PLoSO...853446B. doi: 10.1371/journal.pone.0053446. ISSN 1932-6203. PMC . 3546048 PMID 23335964.