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Clinical data
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CAS Number
PubChem CID
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ECHA InfoCard100.008.387 Edit this at Wikidata
Chemical and physical data
Molar mass287.110 g/mol g·mol−1
3D model (JSmol)
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Brallobarbital was a barbiturate developed in the 1920s.[1] It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine.[2] The long half-life of this combination of drugs tended to cause a hangover effect the next day,[3] and Vesparax fell into disuse once newer drugs with lesser side effects had been developed. Vesperax reportedly was the drug that musician Jimi Hendrix supposedly overdosed on and led to his untimely death. It is no longer made.[4]


  1. ^ US Patent 1869666
  2. ^ Lhermann J. Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (French)
  3. ^ Yih, T. D.; Van Rossum, J. M. (30 September 2009). "Peculiar Pharmacokinetics of Brallobarbital as a Source of Complications in Vesparax® Intoxication". Xenobiotica. 6 (6): 355–362. doi:10.3109/00498257609151647.
  4. ^ Fischbach, R (February 1983). "Efficacy and safety of midazolam and vesparax in treatment of sleep disorders". British Journal of Clinical Pharmacology. 16 (S1): 167S–171S. doi:10.1111/j.1365-2125.1983.tb02290.x. PMC 1428085.