Berzin was born in Paterson, New Jersey, United States. He received his B.A. degree in 1965 from the Department of Oriental Studies, Rutgers University; his M.A. in 1967; and, his Ph.D. in 1972 from the Departments of Far Eastern Languages (Chinese) and Sanskrit and Indian Studies, Harvard University.
In 1998, Berzin moved back to the West and devotes most of his time to preparing his unpublished materials for his Study Buddhism website. The website was chosen in 2011 to be archived as part of the Bodleian Electronic Archives and Manuscripts collection of the University of Oxford.
Berzin is on the Board of Advisors of Tibet House Germany and the International Center for Buddhist-Muslim Understanding of the College of Religious Studies of Mahidol University, Thailand.
"A Buddhist View of Islam" in Islam and Interfaith Relations: The Gerald Weisfeld Lectures 2006 (Perry Schmidt-Leukel and Lloyd Ridgeon, eds.). London: SCM Press, 2007, 187-203. ISBN9780334041320.
"The Sources of Happiness According to Buddhism" in Glück (Andre Holenstein, Ruth Meyer Schweizer, Pasqualina Perrig-Chiello, Peter Rusterholz, Christian von Zimmermann, Andreas Wagner, Sara Margarita Zwahlen, eds.). Bern, Stuttgart, Wien, Haupt Verlag, 2011, 41-52. ISBN9783258076898.