Although Air Liquide's headquarters are in Paris, France, it also has major sites in Japan (ALL) and Houston, TX and Newark, DE, USA. There is an emphasis on research and development (R&D) throughout the Air Liquide company. R&D targets the creation of not only industrial gases, but also gases that are used in products such as healthcare items, electronic chips, foods, and chemicals. The major R&D groups within Air Liquide focus on analysis, bioresources (foods and chemicals), combustion, membranes, modeling, and the production of hydrogen (H2) gas.
1902: Georges Claude and Paul Delorme develop a process for liquefying air to separate the components. First drops of liquid air and creation of the company of the same name. Paul Delorme is the first president.
1906: Launch of international expansion, first in Belgium and Italy, then also in Canada, Japan and Hong Kong.
1945: After the war, Jean Delorme, second president of the Group seeks to restore roads, renovate, and develop the tool industry.
1946: Air Liquide founds La Spirotechnique (now Aqua Lung International), its own division destined to conceive and commercialize regulators and other diving equipment. The same year La Spirotechnique launches the CG45, the first modern regulator to be commercialized. The year 1946 thus represents the beginning of the popularisation of scuba diving.
1957: Launch of great activity and industry networking pipes irrigating several major industrial areas in the world.
1962: Launch of space adventure.
1986: Deployment in the United States with the acquisition of Big Three Industries, a US industrial gas company distributing its gases through a network of pipelines along the Gulf Coast  and new establishments in many countries, particularly in Europe and Asia. Acquisition of SEPPIC, the French specialty chemicals company, as part of its Healthcare World Business Line.
1995: Creation of Air Liquide Health: structure, teams, a gas supply medical equipment and services, fully dedicated to the medical sector, first at the hospital, then to patients' homes.
1996: Acquisition of Schuelke and Mayr in Germany.
2017: Air Liquide signed an agreement with Cargill to build a biodiesel plant in Kansas, US. The operation is planned to start in January 2019 to produce 60M gallons of biodiesel a year. Air Liquide and Cargill has already built six biodiesel plants together worldwide.
Since the 2000 decade, Air Liquide increased significantly its investments in hydrogen production plants, with an increase by more than 50% between 2005 and 2008, making it one of the major segment of its offer. 
In early 2008, Air Liquide entered a long term contract (typically 15 years or more) with Neste Oil’s Renewable Diesel Plant to supply hydrogen.[clarification needed] Air Liquide is building a unit on Jurong Island to provide the means for the deal. They plan to turn the unit into an integrated hydrogen pipeline network that will provide services to regional companies.
In November 2015, Air Liquide announced it would acquire American firm Airgas for a total of $13.4 billion including debt. The Airgas shareholders have approved Air Liquide's acquisition on February 23, 2016. On May 23, 2016, Air Liquide announced the completion of the acquisition of Airgas.
Air Liquide Global E&C Solutions Germany GmbH (formerly Lurgi GmbH)
Air Liquide Global E&C Solutions GmbH (formerly Lurgi GmbH), a German engineering, construction, and chemical process licensing company. has been a part of Air Liquide S. A. since 2007. The head office is located in Frankfurt am Main. Lurgi was the cable address of Metallurgische Gesellschaft founded on 5 February 1897 with an origin dating to the technical branch of Metallgesellschaft, which had been established by Wilhelm Merton in 1881. By the end of World War I, the company had gained a foothold in the steam and absorption business and gathered expertise in the upgrading of solid fuels and the processing of the resulting gaseous and liquid products. As a consequence of this diversification, the company divided into process-specific subsidiaries, which beginning in 1919 traded under the name Lurgi. In 1923, they jointly moved into offices at Gervinusstrasse, Frankfurt am Main. To meet the requirements of the international markets, Lurgi constituted itself as a German stock corporation in 1990. Lurgi operated limited liability companies in chemistry, metallurgy and industry construction; energy and environmental techniques; and gas- and mineral oil techniques. Each company had their own engineering and commercial staff. In 1991, Lurgi pooled its polymer activities by taking over Zimmer AG from the British Davy-McKee AG as the fourth operating company. In 2001 Lurgi sold their metallurgical division (Lurgi Metallurgie) to Outokumpu. After acquisition by Air Liquide, the Zimmer technology portfolio was sold in 2014 to Technip.
Air Liquide Global E&C Solutions Germany today focuses on three primary technology portfolios:
Alternative Technology based upon turning natural gas, coal, biomass into synthetic fuels through gasification, fischer-tropsch and proprietary methanol to synthetic fuels.
Refinery Technology consisting of conventional methods.
Renewable Technologies including biodiesel as well as bioethanol processes.