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Acetohexamide

Acetohexamide
Acetohexamide.svg
Acetohexamide ball-and-stick.png
Clinical data
Trade namesDymelor
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa602021
ATC code
Pharmacokinetic data
Protein binding90%
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.301 Edit this at Wikidata
Chemical and physical data
FormulaC15H20N2O4S
Molar mass324.395 g/mol g·mol−1
3D model (JSmol)
Melting point188 to 190 °C (370 to 374 °F)
  (verify)

Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.

Mechanism of action

Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.[1] The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Risks

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition.[2]

References

  1. ^ "Archived copy". Archived from the original on 2011-11-05. Retrieved 2011-10-26.CS1 maint: archived copy as title (link) – Metformin Side Effects
  2. ^ Medline Plus Archived September 11, 2005, at the Wayback Machine – Acetohexamide