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AL-38022A structure.png
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass231.293 g/mol g·mol−1
3D model (JSmol)
Melting point106 to 107 °C (223 to 225 °F)
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AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications. It acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around 4x less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests on animals, it fully substituted for both DOM and 5-MeO-DMT.[1]

See also


  1. ^ May JA, Sharif NA, Chen HH, Liao JC, Kelly CR, Glennon RA, et al. (January 2009). "Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]". Pharmacology, Biochemistry, and Behavior. 91 (3): 307–14. doi:10.1016/j.pbb.2008.07.015. PMC 3763814. PMID 18718483.