7β-OH-DHEA; 3β,7β-Dihydroxyandrost-4-ene-17-one; Androst-4-en-3β,7β-diol-17-one
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||304.430 g·mol−1|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
7β-Hydroxydehydroepiandrosterone (7β-hydroxy-DHEA; 7β-OH-DHEA), also known as 3β,7β-dihydroxyandrost-4-ene-17-one, is an endogenous, naturally occurring steroid and a metabolite of dehydroepiandrosterone (DHEA). The major metabolic pathway of DHEA outside the liver is via 7-hydroxylation into 7α-OH-DHEA and 7β-OH-DHEA. 7β-OH-DHEA has weak antiestrogenic activity, selectively antagonizing the estrogen receptor ERβ.
he major metabolic pathway for DHEA in extra-hepatic tissues is via 7-hydroxylation ,  and .
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