3D model (JSmol)
|Molar mass||451.348 g·mol−1|
|Appearance||White to beige powder|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) is a selective muscarinic acetylcholine receptor (mAChR) M3 antagonist. It is also able to antagonize M1 receptors but "prefers" M3. It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.
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