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3,3-Diethyl-2-pyrrolidinone

3,3-Diethyl-2-pyrrolidinone
Diethylpyrrolidinone.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.162.031 Edit this at Wikidata
Chemical and physical data
FormulaC8H15NO
Molar mass141.210 g/mol g·mol−1
3D model (JSmol)
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3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans.[2]

References

  1. ^ Hill, MW; Reddy, PA; Covey, DF; Rothman, SM (1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". Journal of Neuroscience. 18 (14): 5103–11. PMID 9651194.
  2. ^ Evason, K; Huang, C; Yamben, I; Covey, DF; Kornfeld, K (2005). "Anticonvulsant medications extend worm life-span". Science. 307 (5707): 258–62. doi:10.1126/science.1105299. PMID 15653505.